Refolding Technologies for Antibody Fragments
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چکیده
منابع مشابه
Refolding Technologies for Antibody Fragments
Refolding is one of the production technologies for pharmaceutical grade antibody fragments. Detergents and denaturants are primarily used to solubilize the insoluble proteins. The solubilized and denatured proteins are refolded by reducing the concentration of the denaturants or detergents. Several refolding technologies have been used for antibody fragments, comprising dilution, dialysis, sol...
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ژورنال
عنوان ژورنال: Antibodies
سال: 2014
ISSN: 2073-4468
DOI: 10.3390/antib3020232